摘要
本文对兰州地区258例各型肝炎进行了抗-HCV检测,结果28例阳性,提示本地区肝炎患者中,约10％为丙型肝炎。在既往诊断为非甲非乙型肝炎中,丙型肝炎占1/4以上。28例HCV感染中,14例为单纯感染,11例与HBV重叠感染,2例与HAV重叠感染,1例与HBV及HDV三重感染。重叠感染者病情较重。通过临床分析,HCV感染在重症肝炎中比例最高(26.7％),其次为肝炎后肝硬化(17.0％)和慢性活动性肝炎(15.8％),说明HCV感染与病情加重及肝炎慢性化,纤维化有关。28例丙型肝炎中19例与输血或血制品有关,提示血源传播是HCV的主要感染途径,有必要对献血员进行抗-HCV筛选。
In order to elucidate the infectious status of HCV in Lanzhou region, anti-HCV were detected in sera from 258 cases of hepatitis patients by ELISA method, the results were that 28 cases were positive for antiHCV (10.9%), among 51 cases of NANBH which diagnosed by exclusive method, 14 patients were positive for anti-HCV (27.4％), This results suggested that the epidemic of HCV in Lanzhou region is serious. After clinical analysising, it was further found that amaong those positive patients, Two were co-infected with HAV, 11 were co-infected with HBV, one was co-infected with HBV and HDV, The detective ratio of antiHCV in FH is most high (26.7％), next is LC (17.0%), CAH(15.8％), AIH(7.9％), HCC(5.9％), CPH(3.6％) in turn. These suggested the infection of HCV, especialy co-infection with other hepatitis virus, maybe corelationship with cirrhosis of liver. Moreover, 19 patients with HCV Infection once tranfused blood, so the blood way may be the predominant infectious way.
出处
《兰州医学院学报》
1992年第4期263-265,共3页
Journal of Lanzhou Medical College
