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胶质细胞源性神经营养因子与癫痫 被引量：2

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摘要 癫痫发作后 ,脑内胶质细胞源性神经营养因子 (GDNF)mRNA的表达及GDNF免疫反应性增强 ,GDNFmRNA的增加可能与海马结构和功能的重组有关。受体Ret与GFRα表达也增强 ,GDNF在癫痫后长时间存在 ,对癫痫发作后神经元的存活与再生有重要意义。并有证据显示GDNF有抗癫痫作用。
作者 冯寅 李为民 吴根诚
机构地区 复旦大学医学院中西医结合系
出处 《国外医学（生理病理科学与临床分册）》 2003年第3期307-309,共3页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
基金 上海市中医药重大项目:SMHB.TCM .Key 2 0 0 0 ( 3)
关键词 癫痫 GDNF GFRα
分类号 R742.1 [医药卫生—神经病学与精神病学]
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参考文献19

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同被引文献22

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  • 8Blesch A, Uy HS, Diergardt W, et al. Neufite outgrowth can be modulated in vitro using a Tetracycline-repressible gene therapy vector expressing human nerve growth faetor[J]. Journal of Neuroscience Research ,2000,59 ( 3 ) :402-409.
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国外医学（生理病理科学与临床分册）
2003年 第3期

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