摘要
目的 总结原发性肝脏淋巴瘤 (PHL)的临床病理学特点。方法 对 10年来我院手术切除的 5例PHL患者的临床资料进行回顾性分析。结果 本组 5例均为男性 ,平均年龄 4 3 6岁 ;肿瘤长径平均 7 8cm。HBsAg阳性 4例 (80 % )。术前误诊为原发性肝癌 4例 ,病理学检查提示为B细胞源性淋巴瘤 2例 ,T细胞源性淋巴瘤 2例 ,何杰金病 1例 ;2例为多原发瘤。结论 肝炎病毒感染可能与PHL发病有关 ;对肝占位性病变伴发热者 ,应警惕PHL的可能 ;手术切除仍为首选治疗方式。
Objective To investigate the clinicopathological features of primary hepatic lymphoma (PHL).Methods Data of 5 PHL cases treated at our hospital between 1998 and 2002 were retrospectively analyzed. Results The patients were all male with a mean age of 43 6 years. Abdominal pain and fever were the most frequent presenting symptoms. Four (80%) were positive for the hepatitis B virus antigen. Tumors were all removed surgically in the 5 patients. Pathologic examination revealed B cell lymphoma, T cell lymphoma and Hodgkin′s disease in 2, 2 and 1 patients, respectively. Moreover, coexistent tumors were incidentally discovered by histology in 2 cases. ConclusionThere seems to be a close relationship between hepatitis B virus infection and the development of PHL; PHL should always be considered in the differential diagnosis for patients presenting with mass lesions in the liver; Surgical resection whenever feasible should be attempted as a part of combination modalities.
出处
《中华普通外科杂志》
CSCD
北大核心
2003年第7期409-411,共3页
Chinese Journal of General Surgery
