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不稳定性心绞痛应用他汀类药物临床观察 被引量:4

Clinical Observation of Effect of Statins on Patients with Unstable Angina Pectoris
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摘要 目的 :探讨洛伐他汀对不稳定性心绞痛 (UA)患者的血脂、心脏缺血事件发生情况的影响。方法 :将UA患者72例分为治疗组和对照组各36例 ,观察用药前后总胆固醇 (TC)、甘油三酯 (TG)、心脏缺血事件发生频率。结果 :治疗组用药后血TC和TG明显下降 ,t分别5.32和5.23(P<0.01) ,治疗组的心脏缺血事件发生率也较对照组明显下降 ( χ2=4.93 ,P<0.05)。结论 Objective:To clinically observe the effect of lovastatin on patients with unstable angina pectoris(UA).Methods:Seventy two patients with UA were randomly divided into a treatment group(n=36)and a control group(n=36).The levels of total cholesterol(TC)and triglyceride(TG)and the frequency of myocardial ischemic event were observed.Results:The levels of serum TC and TG in the treatment group significantly deˉclined after therapy(t=5.32,5.23,P<0.01).The frequency of myocardial ischemic event in the treatment group was significantly lower than that in the control group(χ 2 =4.93,P<0.05).Conclusion:Statins may sigˉnificantly decrease the frequency of myocardial ischemic event in patients with UA.
机构地区 天津市民族医院
出处 《天津医药》 CAS 北大核心 2003年第7期443-445,共3页 Tianjin Medical Journal
关键词 不稳定性心绞痛 他汀类药物 治疗 总胆固醇 甘油三酯 临床观察 angina,unstable lovastatin myocardial ischemia
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参考文献10

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