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Two Novel Antifungal Saponins from Tibetan Herbal Medicine Clematis tangutica 被引量:21

Two Novel Antifungal Saponins from Tibetan Herbal Medicine Clematis tangutica
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摘要 Antifungal assay-guided isolation of the ethanol extract of the aerial parts of Clematis tangutica yielded two novel triterpene saponins. Their structures were determined to be 3-O-a-L-arabinopyranosyl hederagenin 28-O-a-L-rhamnopyranosyl ester (1) and 3-O-b-D- glucopyranosyl(14)-a-L-arabinopyranosyl hederagenin 28-O-a-L-rhamnopyranosyl ester (2) on the basis of spectral data and chemical reactions. Antifungal assay-guided isolation of the ethanol extract of the aerial parts of Clematis tangutica yielded two novel triterpene saponins. Their structures were determined to be 3-O-a-L-arabinopyranosyl hederagenin 28-O-a-L-rhamnopyranosyl ester (1) and 3-O-b-D- glucopyranosyl(14)-a-L-arabinopyranosyl hederagenin 28-O-a-L-rhamnopyranosyl ester (2) on the basis of spectral data and chemical reactions.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2003年第7期707-710,共4页 中国化学快报(英文版)
基金 This work was supported by the Ministry of Science and Technology grant 2001-51 the National Natural Science Foundation of China(30070007),Natural Science Foundation of Yunnan Province(99B0017G).
关键词 Clematis tangutica triterpene saponins HEDERAGENIN antifungal assay. Clematis tangutica triterpene saponins hederagenin antifungal assay.
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参考文献3

  • 1Northwest Plateau Institute of Biology, Academia Sinica, Zang Yao Zhi (Annals of Tibetan herbs, in Chinese), Xining, People's Press, 1991, p. 249.
  • 2H. M. Zhong, C. X.Chen, X.Tian,Y.X. Chui, Y. Z. Chen, Planta Med., 2001, 67 (5), 484.
  • 3H. Kizu, T. Tomimori, Chem. Pharm. Bull., 1982, 30 (9), 3340.

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