摘要
从山东、河北、北京和天津等不同地区分离、鉴定了 4株鸡毒支原体 ,通过体外最低抑菌浓度测定发现泰妙菌素、泰乐菌素、百里霉素、罗红霉素、林可霉素 /壮观霉素合剂、氧氟杀星、乳酸红霉素和盐酸林可霉素对该 4个菌株的最低抑菌浓度 (MIC)平均值分别是 0 .0 0 62 μg/ml、0 .0 1 71 μg/ml、0 .0 682 μg/ml、8.5 2 48μg/ml、8.5 2 48μg/ml、0 .1 0 2 4μg/ml、0 .45 5 0 μg/ml和 1 5 .4944μg/ml,同时发现不同菌株之间的最低抑菌浓度有明显的差异。该试验结果表明鸡毒支原体容易对抗菌药物产生抗药性 ,目前临床预防或治疗鸡毒支原体感染可选用泰妙菌素、泰乐菌素、百里霉素和氧氟杀星等药物 ,而常规使用的红霉素和罗红霉素效果不佳。
strains of Mycoplasma galliseticum are isolated and identified in chickens from different areas.By assaying for the minimum inhibitory concentration(MIC) of antibiotic in vitro,we find that the mean value of MIC of tiamulin,tylosin,kitasamycin,roxithromycin,lincomycin/spectinomycin,ofloxacin,erythromycin lactate and lincomycin hydrochloride for the 4 strains are 0.062 μg/ml、 0.0171 μg/ml、0.0682 μg/ml、8.5248 μg/ml、8.5248 μg/ml、0.1024 μg/ml、0.4550 μg/ml and 15.4944 μg/ml,respectively.Meanwhile the MICs of different strain of Mycoplasma galliseticum are different to be found.This study shows that Mycoplasma galliseticum easily produce drug_resistant strain and tiamulin,tylosin,kitasamycin and ofloxacin can be used in the recent veterinary clinicd therapy and prevention,while MICs of erythromycin and roxithromycin used routinely for Mycoplasma infection in clinic are found to be high.
出处
《中国预防兽医学报》
CAS
CSCD
北大核心
2003年第4期309-312,共4页
Chinese Journal of Preventive Veterinary Medicine
关键词
鸡毒支原体
分离鉴定
最低抑菌浓度
mycoplasma galliseticum
isolation and identification
the minimum inhibitory concentration
