摘要
目的:建立卡托普利片溶出度实验方法;方法:小杯法,60r·min;介质:水,用一阶导数光谱法测定卡托普利的溶出度;结果:30min时的溶出度量不少于75%;结论:本方法准确可用于卡托普利片溶出度的测定。
To establisha a method to determine the dissolution of captopril tablet. Method:Sieve small cup method was used with a speed at 60r. min. Used distilled water as medium and determined the dissolution of captopril tablet by the first derivative spectrophotometry; Result; The dissolution was no less than 75% in 30minutes;Conclusion: This method can determine the dissolution of captopril tablet accurately.
出处
《中国药品标准》
CAS
2003年第3期59-61,共3页
Drug Standards of China
关键词
一阶导数光谱法
测定
卡托普利片
溶出度
抗高血压药物
The first derivative spectrophotometry captopril tablet the determination of dissolution