摘要
目的:建立一种客观的中药质量评价手段,为天南星药材的正确收购及选拨优质药材提供资料。方法:从常用的10种天南星药材中选取与抗肿瘤、镇咳祛痰作用相关的13种成分作为评价指标,并以因子分析方法确定各指标的权数,采用模糊数学方法对这些药材的质量进行综合评价。结果:一把伞南星最佳,其次为象头花和掌叶半夏,粗序南星质最劣。结论:应用因子分析和模糊数学方法建立的数学模型进行中药材质量评价是可行的;建议将掌叶半夏的块茎载入新版药典。
OBJECTIVE: to establish a new, objective approach to the quality appraisal of traditional Chinese medicines and to provide references for selecting and utilizing the resources of medicinal materials 'Tiannanxin'. METHODS: based on the determinion of the bioactive constituents in 10 species of medicinal material 'Tiannanxin' reported by Jishen, et al, 13 constituents related to anticancer, antitussive and expectorant effects, i.e. aspartic acid, asparaginate, β-sitosterol, selenium, molybdeuum, manganese, magnesium, zinc, vanadium, chromium, nickel, cadmium and lead, were selected for appraisal indexes. The factor analysis was used for determinating the weight of these indexes. 10 species of 'Tiannanxin' were comprehensively appraised by fuzzy mathematical method. RESULTS: A. eritbescens was the superior, A. franchetianum second, P. pedatisecta third and A. dilatum the poorest. CONCLUSION: A mathematical model established according to factor analysis and fuzzy mathematics could be sued for the comprehensive appraisal of traditional Chinese medicines. In view of the fact that P. pedatisecta has been cultivated, marketed, exported and used medically for its high quality, it should be acceptd as the original plant of traditional Chinese medicine 'Tiannanxing' in the next edition of Pharmacopoea of the People Republic of China.
出处
《生物数学学报》
CSCD
2003年第2期243-248,共6页
Journal of Biomathematics
关键词
天南星类药材
质量评价
因子分析
模糊数学
中药质量
Medicinal materials Tiannanxing
Factor analysis
Fuzzy mathematics Quality appraisal
