摘要
目的 总结胰腺无功能胰岛细胞瘤的诊疗经验。方法 对我院收治的 32例无功能胰岛细胞瘤的诊断和治疗进行回顾性分析。结果 本组以腹部肿块、腹痛、腹胀、黄疸、腰背痛为主要症状。肿瘤最大径平均为 9cm。 2例患者为多发肿瘤 ,30例单发肿瘤中胰头、体、尾部分别占 4 7%、16 %、31% ;恶性占 6 9% ,良性占 31%。脾胰体尾切除 (34% )和胰头十二指肠切除 (2 2 % )是主要的手术方式。胰瘘 (2 5 % )和切口感染 (9% )是主要的术后并发症。恶性肿瘤术后 1年、3年、5年生存率分别为 90 %、80 %、6 9%。结论 无功能胰岛细胞瘤术前诊断困难 ,手术治疗预后较好。恶性肿瘤有无包膜和切除彻底性是影响预后的主要因素。
ObjectiveTo review the experience on the diagnosis and surgical treatment nonfunctional islet cell tumors (NIT) of the pancreas. MethodsData of 32 NIT patients of the pancreas during the past 46 years in Tianjin Cancer Hospital were analyzed retrospectively.ResultThe average of patients was 32 years old,with female to male ratio of 2.6∶1. The major symptoms included abdominal mass, bellyache, abdominal distension, obstructive jaundice, and back pain. The average diameter of the tumor was 9 cm. Tumors were single in 94% of all cases and multiple in 6%. Tumors located in the head of pancreas in 47% of all cases, in the body in 16%, in the tail in 31%. Tumors were malignant in 69%(22/32) and benign in 31% (10/32 ) .Pancreaticoduodenectomy was performed in 22%, resection of the spleen and pancreatic body-tail in 34%, resection of the body and tail of the pancreas in 16%, biopsy and biliary-enterostomy in 13%, tumor enucleation in 9%, biopsy only in 6%. The main postoperative complications were pancreatic fistulae (25%) and wound infection (9%). The 1? 3 and 5-year survival rates of malignant patients were 90%, 80% and 69%, respectively.ConclusionNIT is often single and large at the time when the patients sought medical consultation. The postoperative prognosis of patients with malignant tumor is favorable.
出处
《中华普通外科杂志》
CSCD
北大核心
2003年第6期340-341,共2页
Chinese Journal of General Surgery
