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脑梗塞患者血清TNF_(-α)、sICAM_(-1)的变化及意义 被引量：1

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摘要 人们很早就发现脑梗塞伴发炎性反应,但直到近年才对其有了较为清楚的认识,肿瘤坏死因子-α(TNF-α)是主要的致炎因子.TNF-α的释放,可激活中性粒细胞,增加白细胞-内皮细胞黏附分子的表达.本研究通过测定急性脑梗死血清中的TNF-α、可溶性细胞间黏附分子-1)(sICAM-1),观察它们的动态变化及二者关系,探讨它们在导致脑缺血损伤中可能的作用机制,为临床的抗炎治疗及对炎症的不同环节加以干预提供理论依据.
作者 赵建华 方树友 王山梅
机构地区 河南省人民医院 郑州大学医学院一附院神经内科
出处 《医药论坛杂志》 2003年第11期64-65,共2页 Journal of Medical Forum
关键词 脑梗塞 血清 TNF—α SICAM-1 统计学分析
分类号 R743.33 [医药卫生—神经病学与精神病学]
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共引文献81

同被引文献23

  • 1王新,黄如训,曾进胜.脑梗死急性期血清MMP-9的动态变化及其与脑梗死分型关系的研究[J].中国神经精神疾病杂志,2005,31(1):20-23. 被引量：48
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医药论坛杂志
2003年 第11期

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