摘要
目的 探讨妊娠妇女不同糖耐量受损 (GIGT)诊断标准与妊娠结局的关系。方法 2 4 5 5例孕妇行5 0 g葡萄糖筛查 ,4 12例异常者行 75 g葡萄糖耐量试验 (OGTT) ,分别比较OGTT第 2小时血糖 6 .7～ 9.1mmol/L者 (GIGT 1组 ) 14 9例、单项值异常者 (GIGT 2组 ) 5 7例、妊娠期糖尿病者 (GDM组 ) 71例及对照组的妊娠预后。结果 GIGT1组、GIGT2组、GDM组都有不同程度的高危因素 ,其妊娠高血压综合征、羊水过多、巨大儿、剖宫产率、新生儿病率 (新生儿窒息、新生儿低血糖、低血钙、新生儿高胆红素血症 )的发生率明显高于对照组 (P <0 .0 5 ) ,并呈递增趋势 ,但GIGT 1组和GIGT 2组间无显著性差异。GIGT1组、GIGT2组在发病的高危因素方面有显著性差异 ,但两组对妊娠结局的影响是一样的。结论 GIGT(1组、2组 )对妊娠可造成不同程度的危害 。
Objective To explore the relationship of different diagnosis standards between gestational impaired glucose tolerance (GIGT) and the pregnancy outcomes.Methods Glucose challenge test (50g) was offered to 2 455 pregnant women and an oral glucose tolerance test (75g) was performed on 412 cases with positive result, the pregnancy outcomes were compared in the 149 cases with 2 hour OGTT value of 6.7～9.1mmol/L (GIGT 1 group),57 cases with single abnormal value of OGTT (GIGT 2 gruop),71 cases with gestational diabetes mellitus (GDM) and control group.Results There were high risk factors in the patients suffered from GDM in GIGT1,GIGT2 and GDM.The incidence of pregnancy induced hypertension syndrome (PIH),polyhydramnios,macrosomia, cesarean delivery rate,neonatal morbidity (neonatal asphyxia,hypoglycemia,hypocalcemia, hyperbilirubinemia) was significantly higher than that of the control group ( P <0.05),and the statistic difference existed in the GIGT1 and GIGT2 groups in high risk factors,but the influence to pregnancy outcome was same in the two groups.Conclusions The GIGT1 and GIGT2 can make a different degree injure in pregnancy.The outcome of GIGT2 and GDM was just alike result.
出处
《北京医学》
CAS
北大核心
2003年第3期185-187,共3页
Beijing Medical Journal
