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动脉瘤性蛛网膜下腔出血后慢性脑积水易患因素分析 被引量:21

Analysis of the factors associated with hydrocephalus after aneurysmal subarachnoid hemorrhage
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摘要 目的 探讨动脉瘤性蛛网膜下腔出血 (SAH)患者慢性脑积水的易患因素。方法 本组 91例患者均由数字减影血管成像 (DSA)明确诊断为颅内动脉瘤 ,并有CT证实的SAH存在 ,应用出血后 3周的CT评价SAH后慢性脑积水。先将可能危险因素与脑积水发生之间进行显著性检验 ,再用多元逐步回归加以明确 ,得到回归方程。结果 动脉瘤性蛛网膜下腔出血患者慢性脑积水的总体发生率为13.2 % ,其易患因素依次是 :①发病后的Hunt&Hess分级 (H H分级 ) ;②出血破入脑室 ;③既往高血压病史 ;④多次出血。结论 动脉瘤性蛛网膜下腔出血后慢性脑积水存在明确的危险因素 ,为多因素共同作用的结果。 Objective To study the factors of chronic hydrocephalus in the patients with aneurysmal subarachnoid hemorrhage (SAH).Methods 91 patients had angiographic verified intracranial aneurysm,SAH was diagnosed upon CT studies.The assessment of hydrocephalus was made on the basis of the beginning and 3 week post SAH CT scans.Univariate analysis was performed to assess the relationship between each factor and the occurence of hydrocephalus;those factor statistically associated with the occurence of hydrocephalus were analyzed further using logistic regression analysis.Results Overall,13.2%(12/91) of the 91 patients developed hydrocephalus.Statistically significant associations of the following factors with hydrocephalus were observed:①Hunt & Hess grade at admission ( P =0.004,B=2.378);②intraventricular hemorrhage at admission ( P =0.008,B=3.281);③preexisting hypertension ( P =0.015,B=3.107);④repeated SAH ( P =0.015,B=2.185).Conclusions Hydrocephalus after aneurysmal SAH seems to have multiple risk factors.Knowledge of these risk factors may help neurosurgeons in the early diagnosis and treatment of this kind of hydrocephalus.
作者 季楠 赵继宗
出处 《北京医学》 CAS 北大核心 2003年第3期151-154,共4页 Beijing Medical Journal
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