摘要
目的 :观察重症胰腺炎早期血液流变与D—二聚体的变化。方法 :将 8例重症胰腺炎列为A组 ,将 1 2例轻症胰腺炎列为B组 ,1 8例正常人列为C组。患者于入院后 2 4h内肘静脉采血 4～5ml,抗凝 ,使用重大维多产全血自动血流变快测仪PASCO - 30 1 0检测各项血流变指标 ,包括 :血浆粘度 (mpa .S) ,全血还原粘度 (mpa .S) ,红细胞聚集指数 ,卡松粘度 (mpa .s) ,纤维蛋白原 (g/L)。使用双抗体夹心ELISA法测定血浆D—二聚体浓度 (mg/L)。结果 :A ,B ,C三组间各项指标比较有差异 (P <0 .0 5或P <0 .0 1 ) ,A组与B组相比 ,或A与C相比 ,各项指标有显著差异 (P <0 .0 5或P <0 .0 1 ) ,B组与C组相比 ,各项指标比较无差异 (P >0 .0 5 )。结论 :重症胰腺炎早期即存在血流变异常与高凝状态 ,因此 ,早期检测急性胰腺炎血液流变与D—二聚体 。
Objective: To investigate the early stage changes of hemorrheology and D-dimer in patients with severe pancreatitis.Methods:Eight patients with severe pancreatitis were divided into group A , twelve patients with mild pancreatitis were divided into group B, and eighteen normal persons were divided into group C. Patients after being admitted to hospital were picked blood 4～5ml in the elbow vein inside 24 hours and resisted congeals,contents of hemorrheology were determined by PASCO-3010, they included plasma viscosity (Mpa.S) , Quan Xue reduction viscosity ( Mpa.S ) ,Erythrocyte aggreggation index, Ka Song viscosity ( Mpa.s ) , and Fibrinogen ( G/L ) .Contents of plasm D-dimer were determined by sandwich ELISA. Result:All quotas of A,B,C groups fairly showed difference each other ( P<0.05or P<0.01 ) . Compared A with B , or compared A with C , all quotas showed notable difference ( P<0.05 or P<0.01 ) . Compared B with C , they did not show any difference (P>0.05).Conclusion: They were abnormal hemorrheology and rapid coaguiation in early state with severe pancreatitis, therefore, early detection of hemorrheology and D-dimer in acute pancreatitis was important to estimate state and prognosis.
出处
《河北医学》
CAS
2003年第5期387-389,共3页
Hebei Medicine
