摘要
目的:评价复方氨酚甲麻口服液的有效性和安全性。方法:采用多中心随机对照开放的试验设计方法,完成可评估病例125例。其中试验组60例,对照组65例,试验药使用复方氨酚甲麻口服液,给药方法为:试验药,口服,每次18ml,每日4次,连续用药3～5d。对照药选用酚麻美敏口服溶液(泰诺),口服,每次10ml,每日4次,连续用药3～5d。结果:试验药和对照药对普通感冒发热、头痛、鼻塞、流涕和咳嗽有明显的效果,有效率分别为94.2％和92.6％,药物不良反应的发生率分别为13.04％和8.82％。结论:复方氨酸甲麻口服液治疗普通感冒安全、有效。
OBJECTIVE: To evaluate clinical efficacy and safety of Fu-fang-an-fen-jia-ma fluid for common cold. METHODS: A total of 125 patients entered a multi-center, randomized, comparative trial. Patients were divided into two groups: one with Fu-fang-an-fen-jia-ma fluid(treatment), po 18ml, once a time, for3 - 5days. Another with Fen-ma-mei-min fluid(Tylenol, control), po 10ml,once a time, for3 -Sdays. RESULTS/The rate of common cold symptoms disappeared were similar in the two groups, the total efficacy rates were 94.2% and 92.6% in the treatment and controlled group,respectively. The incidences of adverse reaction were 13.04% and 8.82% in the two groups. There were no significant differences between the two groups in total efficacy rate and incidence of adverse reaction. CONCLUSION: Fu-fang-an-fen-jia-ma fluid is effective and safe agent in the treatment of common cold.
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2003年第3期167-170,共4页
The Chinese Journal of Clinical Pharmacology
