摘要
目的 :探讨国人Brugada综合征的特点。方法 报道 3例Brugada综合征 ,并复习国内文献报道的 2 0例 ,分析其特点。结果 (1)共 2 3例Brugada综合征中男 2 0例 ,女 3例 ,发病年龄为 9～ 73岁 ,平均40岁。 (2 )临床表现为晕厥 14例 ,其中 4例死亡 ,单纯阵发性心悸、胸闷 3例 ,无症状 6例 ;18个家系中有 5个家系有明确或可疑家族史。 (3)所有病例心电图V1～V3 导联ST段呈尖峰状和 /或马鞍状抬高 ,大多ST段抬高程度多变 ,同时 15例伴典型右束支传导阻滞 ,11例发生室速或室颤 ,其他还可见阵发性房颤、早搏、房室传导阻滞、窦房传导阻滞等心律失常。结论 :(1)国人Brugada综合征临床和心电图特点与国外文献报道相似。 (2 )诊断Brugada综合征主要应根据V1～V3 导联ST段尖峰状和 /或马鞍状抬高的特征性改变 ,晕厥及典型右束支传导阻滞并非必需。 (3)V1～V3 导联段抬高幅度多变是Brugada综合征的一个重要特点 ,ST段抬高程度可能与晕厥发作有关。
Objective To investigate the characteristics of Brugada Syndrome in China.Method 3 cases of Brugada Syndrome are reported,and 20 cases reported in Chinese Journal are reviewed.Results (1)Males(n=20) outnumber females(n=3) by far,and age distribution reveals a peak around the fourth decade (range 9 to 73 years).(2)14 patients present with syncope,4 out of which suffer from sudden death;3 patients present with palpitation or chest closed;while 6 patients are asymptomatic.Of 18 family,5 family histories are suspected or confirmed.(3)The electrocardiogram of all patients is abnormal,displaying right precordial (leads V 1 to V 3)convex curved or/and saddle shaped-type ST-segment elevation in all patients,and the magnitude of the ST-segment shift in most patients;typical right bundle-branch block in 15 patients;paroxysmal ventricular tachycardia or ventricular fibrillation in 11 patients;and paroxysmal atrial fibrillation,premature beat,atrioventricular block,sino-auricular block individual.Conclusions (1)The characteristics of Brugada Syndrome in Chinese is similar to that in foreigner.(2)The diagnosis of Brugada Syndrome is based on the special pattern of ST-segment elevation in leads V 1 to V 3,but is not syncope or right bundle blanch block.(3)The variability of the magnitude of the ST-segment elevation is the important character of Brugada Syndrome,and the magnitude of the ST-segment shift may relate to the occurrence of syncope.
出处
《临床心电学杂志》
2003年第2期93-95,共3页
Journal of Clinical Electrocardiology
