摘要
目的 探讨影响唾液腺粘液表皮样癌患者术后生存的临床病理因素。方法 回顾经首次手术治疗且有完整随访资料的唾液腺粘液表皮样癌患者 70例的临床资料 ,对各项指标采用乘积限法 (Kaplan_Meier)估计各时点的生存率 ,同时进行序检验 (Logranktest)各组间差异 ,最后进入Cox比例风险模型 (CoxRegression)做多因素分析。全部资料通过SPSS软件完成。结果 70例唾液腺粘液表皮样癌患者 ,术后 3、5、1 0年生存率分别为 90 6 6 %、88 85 %、86 6 3%。肿瘤直径小于等于 4cm、术前区域淋巴结无转移、临床处于早期 (Ⅰ、Ⅱ期 )、高分化、术后无复发和转移的患者生存期明显长于肿瘤直径大于 4cm、术前区域淋巴结有转移、临床晚期 (Ⅲ、Ⅳ期 )、低分化、术后出现复发及转移的患者。结论 TNM分类、临床分期。
Objective\ To study the clinico pathologic factors influencing postoperative survival rate in mucoepidermoid carcinoma of salivary glands.Methods\ A retrospective study of seventy patients with mucoepidermoid carcinoma of salivary glands has been carried out. All cases underwent primary surgical resection in our hospital were followed up and clinicopathologic factors influencing the postoperative survival rate of patients were investigated. Statistical analysis was conducted using a computer program (SPSS). The data were statistically treated according to the Kaplan_Meier method. The Log rank tests were employed to assess the statistical significance of various groups.Results\ The 3_, 5_ and 10_year overall survival rate were 90 66%, 88 85% and 86 63%, respectively. The patients with tumors′ diameter less than 4 cm, early clinical stage (stage Ⅰand Ⅱ), well differentiated tumor cells, without lymph nodes involvement, without local recurrence and metastasis after primary surgical resection had a long survival term. The patients with tumors′ diameter more than 4 cm, with lymph nodes involvement, advanced clinical stage (stage Ⅲ and Ⅳ), poor differentiated, with local recurrence and metastasis after primary surgical resection demonstrated a short survival term.Conclusion\ TNM and clinical stage, the degree of differentiation, with or without local recurrence and metastasis after primary surgical resection are the important factors influencing the postoperative survival time.\;
出处
《华西口腔医学杂志》
CAS
CSCD
北大核心
2003年第3期191-193,共3页
West China Journal of Stomatology
关键词
唾液腺
粘液表皮样癌
术后
生存
病理因素
mucoepidermoid carcinoma
\ salivary gland
\ survival
\ clinicopathologic factors\
