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钬激光联合膀胱灌注治疗浅表性膀胱肿瘤(附30例报告) 被引量:27

Holmium:YAG laser resection combined with intravesical chemotherapy for superficial bladder tumor (report of 30 cases)
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摘要 目的 总结应用钬激光 (Ho :YAG激光 )治疗浅表性膀胱肿瘤的疗效。 方法 采用钬激光经尿道切除肿瘤 ,联合术后膀胱灌注治疗浅表性膀胱肿瘤 30例。男 2 5例 ,女 5例。平均年龄 5 4岁。肿瘤单发 15例、多发 15例。病理分级G1~G2 ,分期T1~T2 。肿瘤直径 0 .2~ 3.5cm。 结果 手术均一次成功 ,术后创面基底及创缘病理检查无残余肿瘤 ,术后均行吡柔比星膀胱灌注化疗。手术时间平均 18min ,术中平均出血量 <15ml,无膀胱穿孔或术后继发性出血等严重并发症。 30例随访 3~ 14个月 ,平均 7.5个月 ,复发 1例 ,复发率 3%。 结论 经尿道钬激光切除膀胱肿瘤操作简单 ,疗效确切 ,术中、术后无严重并发症 ,是治疗浅表性膀胱肿瘤的一种理想手术方法。 Objective To evaluate Ho:YAG laser in the treatment of superficial bladder tumors. Methods 30 patients with superficial bladder tumors underwent endoscopic holmium laser resection with postoperative intravesical instillation therapy.There were 25 male patients and 5 famale with an average age of 54.The growth has been single in 15 and multiple in 15.The diameter of the tumor was 0.2~3.5 cm with the pathology grade G 1~G 2 and clinical stage T 1~T 2. Results The procedure has been successful in all and cold cup biopsies of the tumor base and incisal margin were negative.The mean resection time was 18 minutes,the mean volume of bleeding was less than 15 ml and no intraoperative bladder perforation or secondary hemorrhage occurred.All patients have been followed up for 3 to 14 months with a mean of 7.5 months.One patient (3%) had out-of-field recurrence. Conclusions Ho:YAG laser resection of bladder tumor (HoLRBt) provides an useful clinical therapeutic method that has the advantages of precise resection,simple technique,as well as no serious intraoperative or delayed complications.
出处 《中华泌尿外科杂志》 CAS CSCD 北大核心 2003年第6期380-382,共3页 Chinese Journal of Urology
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