摘要
目的:研究心得安试验前后QT离散度(QTd)变化,探讨QTd的本质及评价其临床应用价值。方法:于经冠脉造影及其他检查除排除器质性心脏病,静息心电图有T波低平、双向、倒置或有u波的186例患者,观察心得安试验前、后QTd的变化。结果:(假定QTd>50ms为异常)78例心得安试验阳性者QTd异常率试验前、后分别为83.3％,11.5％,有显著差异(P<0.01);108例心得安试验阴性者QTd异常率试验前、后依次为77.8％,74.1％,无显著差异(P>0.05)。两组QTd异常率试验前无显著差异,试验后有显著差异(P<0.01)。结论:非器质性心脏病心得安试验QTd变化提示QTd异常不能作为反映心肌复极的不均一性指标,预测恶性心律失常或心脏猝死,而只是反映T波非特异性异常的一个粗浅的量化指标,对QTd的临床应用宜慎重。
Objective: To study QT dispersion changed during the inderal-test and evaluate its clinical significance in patients. Methods: All 186 subjects underwent inderal-test and their QT intervals were measured manually. The value of QTd was calculated as a difference between the longest and the shortest measured value in each of the 12 ECG leads. Among 186 patients certificated without heart disease underwent coronary angiography and other examines. ECG of 78 patients was abnormal of T wave before inderal-test and was normal after test. ECG of 108 patients was abnormal of T wave before and after inderal-test. Results; If QTd>50 ms was abnormal, the incidence of abnormal QTd was 83-3% and 11.5% respectively (P<0. 01) before and after inderal-test in 78 patients with inderal-test positive. Incidence of abnormal QTd was 77. 8% and 74. 1% (P>0. 05) respectively before and after inderal-test in 108 patients with inderal-test negative. Incidence of abnormal QTd between two groups was no significant difference before inderal-test and had significant difference after test. Conclusion: Increased QT dispersion is not associated with heart disease and an increased risk for ventricular arrhythmias and sudden death. Abnormal QTd cannot forecast the patients' prognosis. At present, the QTd should be read with caution.
出处
《心血管康复医学杂志》
CAS
2003年第3期206-208,共3页
Chinese Journal of Cardiovascular Rehabilitation Medicine
