摘要
目的探讨头颅局部亚低温治疗急性进展性脑梗死的临床疗效。方法将 6 0例急性进展性脑梗死患者随机分为观察组 (30例 )和对照组 (30例 )。观察组在药物治疗基础上加用亚低温治疗 ,对照组为单纯药物综合治疗。 72 h和 7d后对两组患者进行脑梗死体积及瘫痪肢体神经功能缺损评定。结果治疗 72 h、7d后 ,观察组患者的脑梗死体积明显小于对照组 (P<0 .0 1) ,两组患者的瘫痪肢体神经功能评分有高度显著性差异 (P<0 .0 1)。结论头颅局部亚低温治疗可以减轻急性进展性脑梗死患者的脑水肿 ,有脑保护作用 ,为应用低温治疗脑梗死提供了重要的理论依据。
ObjectiveTo study effects of treating acute progressive cerebral infarction by the brain-located mild hypothermia therapy.Methods60 patients were randomly divided into the treatment group (30 cases) and the control group (30 cases). Drugs were used in both groups, and the located mild hypothermia therapy was only applied in the treatment group. After 72 hours and 7 days, the volume of cerebral infarction and the nerve function deficiency (NFD) scores of hemiplegic limbs were compared.ResultsThe volume of cerebral infarction of the treatment group was significantly smaller than that of the control group ( P< 0.01 ). There were significant differences on the neurological impairment scores between two groups ( P<0.01).Conclusions The brain-located mild hypothermia therapy can reduce hydrocephalus of patients with acute progressive cerebral infarction, and have brain protection. These results provide an important theoretical foundation for the treatment of cerebral infraction with low-temperature therapy.
出处
《中国康复理论与实践》
CSCD
2003年第6期326-327,共2页
Chinese Journal of Rehabilitation Theory and Practice
关键词
局部亚低温
急性进展性脑梗死
治疗
located mild hypothermia
acute progressive cerebral infarction
treatment
