摘要
目的 观察经皮肝穿刺射频消融术对肝癌的热消融作用及其适应证。方法在局麻或硬膜外麻醉下及B超引导下,射频穿刺电极经皮穿刺入肝癌瘤体内,对其进行消融。结果60例患者的96个瘤体中,直径<3.5 cm的41个(42.7％)瘤体获得一次手术热消融。其中,38个完全缓解(CR),3个部分缓解(PR),有效率(CR+PR)100％。41个瘤体中,36个经CT或MRI随访6～24个月,未见复发。直径≥3.5 cm～12 cm的55个(57.3％)瘤体可分2,3次手术,术后1～3个月CT或MRI提示,瘤体CR 2个,PR 37个,CR+PR70％。结论经皮肝穿刺射频消融术治疗肝癌,对直径<3.5 em的瘤体疗效可靠,对直径≥3.5 cm的瘤体仍具有部分热消融的作用。
Objective To observe the curative effect of percutaneous radio frequency ablation (PRFA) on hepatocellular carcinoma. Methods Under local or epidural anaesthesia, radio frequency electrodes were percutaneously introduced with ultrasound guide into the tumor in the liver for ablation. Results Among the 96 hepatic cancer lesions in 60 patients, 41(42.7%) with diameter < 3.5 cm were ablated by one session. The effective rate (CR+PR) was 100% (41/41) with CR 92.6% (38/41 )and PR 7.3% (3/41). During the 6-24 month follow up of these lesions, 36(87.8%)of these 41 patients showed no recurrence by CT or MRI. Fifty-five (57.3% )lesions with diameter 3.5 cm were ablated by two or three sessions, with CR 3.6% (2/ 55), PR 67.3% (37/55) and CR+PR 70.9% (39/55) by CT or MRI in 1 to 3 months after the treatment. Conclusion Percutaneous radio frequency ablation is effective on liver tumor with < 3. 5 cm. It is partly effective on lesions with 3.5 cm < 12 cm.
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
2003年第1期88-90,共3页
Chinese Journal of Oncology
