摘要
目的 :寻找简单、方便、有效的预防产后出血的方法。方法 :将 30 0例无合并症产妇分成 3组 ,均于胎儿娩出后立即给药。A组 10 0例给缩宫素 2 0U ,静脉注射 ;B组 10 0例给米索前列醇 4 0 0μg ,口服 ;C组 10 0例给卡前列甲酯栓 1mg置入直肠内。比较 3组产后 2h出血量。结果 :A组的产后 2h出血量为 (2 5 1±s 71)mL ,B组和C组的产后 2h出血量分别为 (15 9± 6 7)mL和 (15 0± 73)mL ,A组明显多于B组和C组 ,差异有显著意义 (P<0 .0 1)。而B组和C组间差异无显著意义 (P >0 .0 5 )。结论 :米索前列醇。
AIM: To seek a simple and effective method to prevent postpartum bleeding. METHODS: Three hundred normal parturients were divided into three groups. All of them were given medicine immediately after the delivery of the fetus.One hunderd parturients in group A ,were given 20 U oxytocin iv. One hunderd parturients in group B were given misoprostol 400 μg, po . One hunderd parturients in group C were given methyl carprost suppository 1 mg via the rectum. The amount of postpartum bleeding within 2 h of three groups was compared. RESULTS: The mean amount of bleeding for parturients who recived oxytocin was (251± s 71) mL, in contrast ,the mean amount of bleeding for parturients who recived misoprostol and methyl carprost were (159±67) mL and (150±73) mL. The differences in the amount of bleeding among group A,B and C, were significant ( P <0.01), whearas differences between group B and group C were not significant ( P >0.05).CONCLUSION: Both misoprostol and methyl carprost suppository can prevent postpartum bleeding effectivly.
出处
《中国新药与临床杂志》
CAS
CSCD
北大核心
2003年第6期347-349,共3页
Chinese Journal of New Drugs and Clinical Remedies
关键词
产后出血
预防
缩宫素
米索前列醇
卡前列甲酯栓
oxytocin
misoprostol
methyl carboprost suppository
postpartum hemorrhage
