摘要
目的:探讨经鼻持续气道正压通气(nCPAP)治疗,对阻塞性睡眠呼吸暂停综合征(OSAS)合并高血压患者动态血压的影响。方法:22例男性患者行多导睡眠图(PSG)监测及动态血压检查确诊为OSAS合并高血压的患者,观察nCPAP治疗前后患者动态血压、多导睡眠图等多项指标变化。结果:nCPAP治疗后患者PSG参数明显改善:睡眠时最低SaO_2从(71.0±12.3)％上升到(91.7±7.3)％(P<0.01);RDI显著降低;同时24小时血压明显下降,治疗前血压(16.5±1.6/11.6±2.3Kpa),治疗后血压(13.7±1.5/9.3±1.4Kpa)(P<0.01)。结论:经鼻持续气道正压通气治疗阻塞性睡眠呼吸暂停综合征,不但可以纠正患者的呼吸暂停,改善临床症状,而且可能降低患者的血压。
Objective: To evaluate the effect of nasal continous positive airway pressure(nCPAP) on 24-hour ambulatory blood pressure in obstructive sleep apnea syndrome(OSAS) by polysomanography.Methods: We use nCPAP treating 22 male patients with OSAS. According to the result of polysomonography and 24- hour ambulatory blood pressure, we evaluate the therapeutic effect. Resul ts: After nCPAP treatment, the result of PSG monitor present: the lowest SaOz increased from(71. 0 ± 12.3)% to (91.7±7.3)% during sleep; RDI decreased obviously too.At the same time, blood pressure fell significantly in patients who were treated:24-hour mean BP(systole/diastole) decreased from 16. 5± 1. 6/11. 6±2. 3 Kpa to 13. 7± 1. 5/9. 3± 1. 4 Kpa(P<0. 01) .The reduction in 24-hour mean systolic BP occurred during both day and night.Conclusion: nCPAP can im-prove airway obstruction and exert beneficial effect on diurnal and nocturnal hypertension.
出处
《现代医药卫生》
2003年第6期668-669,共2页
Journal of Modern Medicine & Health
