摘要
目的 :解读ALLHAT(抗高血压部分 )和LIFE试验 ,以供临床医师合理用药参考。方法 :根据ALLHAT(抗高血压部分 )和LIFE试验的研究方法和结果进行分析、讨论。结果与结论 :( 1)ALLHAT充分说明了严格控制高血压的重要性和有效控制高血压的困难性 ,同时 ,应慎重解释氨氯地平和赖诺普利治疗组发生心力衰竭多于氯噻酮组的试验结果 ;( 2 )LIFE试验是第一个显示血管紧张素受体拮抗剂优于β受体阻滞剂的试验 ,它的结果具有重要临床意义。
OBJECTIVE:Commentating ALLHAT(the part of anti-hypertension treatment) and LIFE,to surpply clinician reference to use drug in reason.METHODS:According to the data of ALLHAT(the part of anti-hypertension treatment) and LIFE to analysis and debate.RESULTS & CONCLUSIONS: (1)ALLHAT explained the importance and difficulty of controlling hypertension strictly and availability .And we should explain the results with caution about that the ratios of patients who were treated with amlodipine and lisinopril occurring heart failure are more than that of with chortalidone.(2)LIFE is the first trial that shows angiotensin receptor antagonists excelled the β receptor blokers,and it shows important clinical meaning.
出处
《中国医院用药评价与分析》
2003年第1期8-10,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
