摘要
抗精子抗体 (AsAb)是血 睾屏障被各种机制破坏 ,导致精子免疫性抗原暴露于免疫系统诱发免疫反应而产生。AsAb可以影响精卵的结合和胚胎的发育而引起不育。现就文献中AsAb的病因。
The formation of antisperm antibodies (AsAb) results from the disruption of the blood-testis barrier by a variety of mechanisms, which leads to exposure of immunogenic sperm antigens to the immune system and initiates an immune response. AsAb can impair the fusion of sperm and egg and even the embryo development, resulting in infertility. The etiology of AsAb, effect of AsAb on assisted reproduction and treatment of AsAb in the literature are reviewed in this article. Natl J Androl,2003,9(3):214-217
出处
《中华男科学杂志》
CAS
CSCD
2003年第3期214-217,共4页
National Journal of Andrology
关键词
抗精子抗体
免疫反应
辅助生育
Antisperm antibody (AsAb)
Immune response
Assisted reproduction