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丁螺环酮治疗广泛性焦虑症临床分析 被引量:4

A clinical trial of buspirone in the treatment of generalized anxiety disorder
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摘要 目的 :探讨丁螺环酮治疗广泛性焦虑症的疗效和不良反应。 方法 :对 5 0例临床诊断为广泛性焦虑症的病人用丁螺环酮治疗 4周 ,采用Hamilton焦虑量表 (HAMA)及副反应量表 (TESS)进行评定。 结果 :丁螺环酮治疗广泛性焦虑症的有效率 90 7% ,显效率 5 5 9% ;主要不良反应是轻微的口干及头昏和头晕等 ,偶可致窦性心律不齐。 结论 :丁螺环酮治疗广泛性焦虑症有效 。 Objective:To evaluate the therapeutic effect and side effects of buspirone in the treatment of generalized anxiety disorder (GAD). Method:50 patients with a diagnosis of generalized anxiety disorder according to CCMD 2 R were treated with buspirone for four weeks.Effects and side effects were evaluated with Hamilton anxiety scale (HAMA) and treatment emergent symptom scale (TESS). Results:The rate of full recovery from GAD was 55 9% with buspirone,and improvement rate was 90 7%.It produced slight thirst,dizziness and ECG abnormality. Conclusion:It is suggested that buspirone is effective in the treatment of GAD and produceds fewer side effects.
出处 《临床精神医学杂志》 2003年第3期157-158,共2页 Journal of Clinical Psychiatry
关键词 广泛性焦虑症 丁螺环酮 Generalized anxiety disorder Buspirone
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参考文献2

  • 1Staid SM. Mixed depression and anxiety: serotoninIA receptors as a Common pharmacologic link. J Clin Psychiatry, 1997,58 ( suppl 8) : 20.
  • 2Debra A, Glitz Robert Pohl. 5-HTIA patial agonists drugs. Leading Article, 1991,141 : 11.

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