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疣状皮肤结核患者皮损中结核杆菌DNA的检测 被引量:2

Detection of Mycobacterium Tuberculosis DNA in the Skin Lesions of Patients with tuberculosis verrucosa cutis
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摘要 本文采用PCR技术 ,对 10例病史 2年以上的疣状皮肤结核患者皮损进行了结核杆菌DNA检测 ,结果显示 10例患者 1例阳性 ,而作为阳性对照的 4例淋巴结结核组织 3例阳性 ,2例正常组织均为阴性。 Applying PCR technique to detect mycobacterium tuberculosis DNA in the skin lesions of ten patients with tuberculosis verrucosa cutis.The history of all patients is above two years.The results showed that only one skin lesion was positive detected in ten patients and three patients were positive detected in four patients with lymphoid tuberculosis as posivive controls and tow normal skin lesions as negative controls were all negative.The results indicate that the mycobacterium tuberculosis was seen only occasionally in the skin lesion of tuberculosis verrucosa cutis in late stage.
出处 《皮肤病与性病》 2003年第2期4-5,共2页 Dermatology and Venereology
关键词 疣状皮肤结核 结核杆菌 DNA 检测 聚合酶链反应 Tuberculosis verrucosa cutis,Mycobacterium tuberculosis,Polymerase chain reaction(PCR)
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  • 1冉玉平,周光平,郭在培,步宏,杨秀英,邹敏.应用聚合酶链反应诊断疣状皮肤结核1例报告[J].临床皮肤科杂志,1994,23(5):250-251. 被引量:3
  • 2步宏,覃扬.用PCR技术对淋巴结核进行病原学检查的初步研究[J].中华病理学杂志,1991,20(4):260-262. 被引量:12
  • 3Champion RH,Burton JL,Burns DA,et al.Textbook of Dermatology.6th ed,Oxford:Black well scientific publications,1998,1991-1992.
  • 4Arora SK,Kumar B,Sehgal S.Development of a polymerase chain reactiondot-blotting system for detecting cutaneous tuberculosis.Br J dermatol,2000, 142 (1): 72-76.
  • 5Tan SH,Tan BH,Goh CL,et al.Detection of mycobacterium tuberculosis DNA using polymerase chain reaction in cutaneous tuberculosis and tuberculids .Int J Dermatol,1999, 38 (2) : 122- 127.

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