摘要
应用蚕豆根尖微核技术对10份矿尘样品、黄曲霉毒素B_1(AFB_1)和15份真菌提取物进行诱变性研究,结果有10份矿尘、AFB_1和5种真菌提取物能明显诱发蚕豆根尖细胞微核率的增高;对其中5~#矿尘、AFB_1和杂色曲霉提取物进行剂量效应测定,显示了良好的剂量效应关系,提示具有诱变活性,这对当地的肿瘤发病率可能起重要作用。说明蚕豆根尖微核技术对研究环境诱变剂不失为一种有效的手段。
Micronucleus test in vicia foba root tips was performed for 10 mine dust tamples. AFB 1 and 15 fungal extracts. The results showed that 10 (100%) mine dust, AFB1 and 5(33.3%) fungal extracts significantly increased the frequency of micronucleated cells in vicia faba root tips with a clearr dose-effect relationship suggesting that these samples had mutagenic activity and the relevant environmental factors might be responsible for the incidence of lung cancer in he mine area and liver cancer in Fu-shui county. Thus micronucleus test in vicia faba root tips proved to be an effective method in the research of environmental muta-gens.
出处
《环境科学》
EI
CAS
CSSCI
CSCD
北大核心
1992年第4期56-59,共4页
Environmental Science
关键词
蚕豆根尖
微核
矿尘
诱变性
vicia faba root tips, micronucleus, mine dust, fungal extracts, mutagenicity.
