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生长激素基础值及其分泌功能的观察

The Observation in Basal Level & Secretory Function of Growth Hormone
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摘要 对正常人和侏儒症、肢端巨大症等患者进行hGH水平测定及功能试验。结果36例正常人hGH基础值多数小于5μg/L(0.6±0.83),100例正常人活动值多数小于10μg/L(2.36±3.81)。垂体性侏儒症患者hGH一般低于正常,对胰岛素低血糖,多巴胺兴奋试验缺乏正常反应。肢端巨大症患者hGH均高于20μg/L,且不受葡萄糖抑制。提示hGH水平测定及分泌功能试验有助于侏儒症和肢端巨大症的诊断及判断后者活动与否。溴隐亭敏感试验有助于肢端巨大症疗效预测。 This paper reports the determination of hGH level & its secretory function in normal people & patients with dwarfism & acromegaly. The result showed hGH basal level was mostly smaller than 5μg/L(0.6±0.83)in 36 normal people. The level of activity in 100 normal people was mostly smaller than 10μg/L(2.36±3.81). hGH was generally under the normal level & tests of insulin hypoglycemia and of dopamine excitation were lack of normal in patients with pituitary dwarfism. In patients with acromegaly, hGH is all higher than 20μg/L & is not suppressed by glucose. It is suggested that the tests of hGH & of secretory function are of Some help to diagnosis for patients with dwarfism & acromegaly & can judge whether the latter is active or not.The susceptible test of Bromecriptine is of help to measuring the effect of treatment.
出处 《安徽医科大学学报》 CAS 1989年第1期24-28,共5页 Acta Universitatis Medicinalis Anhui
关键词 生长激素 分泌功能 侏儒症 somatotropin/diag use dwarfism/diag acromegaly/diag diagnosis endocrine diseaes
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