摘要
目的 探讨胼胝体前部胶质瘤的临床特点、应用显微手术切除的可行性及其预后。方法 对我院1998年 1月至 2 0 0 2年 6月收治的 2 0例经手术及病理证实的胼胝体前部胶质瘤患者进行回顾性分析。结果 手术全切除 12例 ,次全切除 6例 ,活检 2例。术后无 1例死亡 ,3例术后出现短暂性失语和反应迟钝 ,2例术后癫小发作 ,1例术后出现短暂性右上肢无力 ,14例术后恢复良好。 10例随访 6个月至 4年 ,平均生存期 70周。结论 胼胝体受侵是一种对胶质瘤患者预后不利的因素。对于大部分病例 ,全切除或次全切除肿瘤取得良好的临床效果是完全可能的。经胼胝体前部入路是治疗该区肿瘤的一个安全可行的选择。
Objective To evaluate clinical feature and surgical treatment feasibility of anterior callosal glioma with microscope technique and prognosis of the patients. Methods 20 cases with anterior callosal glioma were operated and analyzed retrospetively in our hospital from January 1998 to June 2002. Results 12 patients underwent total surgical treatment, 6 patients with subtotal surgical treatment and 2 patients with biopsy only. There were no operative mortality. The patients postoperative recovery was fine in 14 of 20 cases. But there were transient aphasia and reaction dullness in 3 cases, minor epilepsy in 2 cases and right upper extremity asthenia in 1 case. The median survival time was 70 weeks in 10 cases who were followed. Conclusions The results indicate that corpus callosum involvement is a poor prognostic factor for patients with glioma; In most cases its possible to remove these tumors totally or sub totally with good clinical effect. Anterior transcallosal approach is a safe, feasible alternative in the management of the tumors in these regions.
出处
《中国神经精神疾病杂志》
CAS
CSCD
北大核心
2003年第3期170-171,共2页
Chinese Journal of Nervous and Mental Diseases
