摘要
目的:总结酚妥拉明与多巴胺伍用治疗慢性肺心病心力衰竭的疗效。方法:30例肺心病顽固性心衰患者,均在抗感染、吸氧、利尿、强心等综合治疗后,心衰无好转时加用酚妥拉明与多巴胺静脉滴注,每日一次,连用7至10天。用药前后记录血压、心率、尿量。结果:一疗程后心率明显减慢,尿量明显增加与治疗前相比有非常显著差异(P<0.01)。血压与治疗前无明显差异(P>0.05)。总有效率达86.6%(显效46.6%,有效40%)。结论:酚妥拉明与多巴胺伍用治疗慢性肺心病顽固性心衰,疗效确切,副作用少,在临床上有一定的使用价值。
Objective: To study the effect of phentolamine combined with dopamine in the treatment of heart failure of chronic cor pulmonale. Methods:The heart failure in 30 patients with intractable heart failure of chronic cor pulmonale was not improvement after the complex treatment such as anti -infection oxygen uptake>diuresis>cardiotonicness and so on, the phentolamine and dopamine were used by intravenous drip once a day for 7-10 days. The blood pressure, heart rate and urinary output were recorded before and after medication. Results: Compared with the pretreatment, the heart rate was obviously decreased, the urinary output was obvioushy increased a course after treatment, with a significant difference between them(P <0.01) .There was no significant difference in the blood pressure before and after treatment.The total effective rate was 86.6% (excellent effect 46. 6% , efficacy 40%). Conclusion:Phentolamine combined with dopamine for treating intractable heart failure of chronic cor pulmonale is really efficacious, with less side effect. It is valuable to applicating in clinic.
出处
《现代医药卫生》
2003年第5期536-537,共2页
Journal of Modern Medicine & Health