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酚妥拉明与多巴胺伍用治疗慢性肺心病心力衰竭 被引量:3

Experience of phentolamine combined with dopamine for treating heart failure of chronic cor pulmonale in 30 cases.
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摘要 目的:总结酚妥拉明与多巴胺伍用治疗慢性肺心病心力衰竭的疗效。方法:30例肺心病顽固性心衰患者,均在抗感染、吸氧、利尿、强心等综合治疗后,心衰无好转时加用酚妥拉明与多巴胺静脉滴注,每日一次,连用7至10天。用药前后记录血压、心率、尿量。结果:一疗程后心率明显减慢,尿量明显增加与治疗前相比有非常显著差异(P<0.01)。血压与治疗前无明显差异(P>0.05)。总有效率达86.6%(显效46.6%,有效40%)。结论:酚妥拉明与多巴胺伍用治疗慢性肺心病顽固性心衰,疗效确切,副作用少,在临床上有一定的使用价值。 Objective: To study the effect of phentolamine combined with dopamine in the treatment of heart failure of chronic cor pulmonale. Methods:The heart failure in 30 patients with intractable heart failure of chronic cor pulmonale was not improvement after the complex treatment such as anti -infection oxygen uptake>diuresis>cardiotonicness and so on, the phentolamine and dopamine were used by intravenous drip once a day for 7-10 days. The blood pressure, heart rate and urinary output were recorded before and after medication. Results: Compared with the pretreatment, the heart rate was obviously decreased, the urinary output was obvioushy increased a course after treatment, with a significant difference between them(P <0.01) .There was no significant difference in the blood pressure before and after treatment.The total effective rate was 86.6% (excellent effect 46. 6% , efficacy 40%). Conclusion:Phentolamine combined with dopamine for treating intractable heart failure of chronic cor pulmonale is really efficacious, with less side effect. It is valuable to applicating in clinic.
作者 张广云
机构地区 云南省冶金医院
出处 《现代医药卫生》 2003年第5期536-537,共2页 Journal of Modern Medicine & Health
关键词 酚妥拉明 多巴胺 治疗 慢性肺心病 心力衰竭 疗效 Phentolamine Dopamine Cor pulmonale Intractable heart failure
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