摘要
从IL-15的组织分布、表达调控及具体生物学功能等方面对IL-15与自身免疫病(autoimmune disease,AID)的关系进行分析和阐述,并列举了5种与IL-15相关的AID及4种以IL-15/IL-15R为靶向的AID治疗策略。
This review attempts to define the relationship between IL-15 and autoimmune disease (AID) from IL-15's tissue distribution, expression regulation and biologic function. Meanwhile, five IL-15 dysregu-lation-related AIDs and four IL-15/IL-15R-targeted AID therapies are discribed.
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
2003年第2期228-232,共5页
Acta Academiae Medicinae Sinicae