摘要
用间接免疫荧光法检测了资料较全的77例肝细胞癌病人血清中的三种自身抗体:抗核抗体(ANA)、抗平滑肌抗体(SMA)和抗线粒体抗体(AMA)。发现不论是在Ⅰ期、Ⅱ期和Ⅲ的肝细胞癌病人ANA和SMA均明显增高;而肝硬化病人的AMA高于肝细胞癌患者,这对于指导临床诊断和治疗以及预后判断有一定的参考价值。
Seventy seven cases of hepatocellular carcinoma with more comprehensive data in our hospital were selected to be detected their autoantibodies, among thich the antinuclear antibody(ANA), the smooth muscle autibody(SMA)and the antimitochondrial antibody(AMA) were mainly detected. It was found that both ANA and SMA in the blood serum of the patients with hepatocellular carcinoma was obviously increased no matter whether the patients was in the first,second or third stage of hepatocellular carcinoma while the AMA in patients with cirrhosis was far higher than that of patients with hepatocellular carcinoma. The result is of great importance in guiding clinical diagnosis and trestment, and helping doctors observe the therapeutic effectiveness and estimate prognosis.
出处
《河南肿瘤学杂志》
1992年第3期14-16,共3页
Henan Journal of Oncology
关键词
肝细胞癌
自身抗体
肝肿瘤
hepatocellular carcinoma
autoantibody
immunofluorescence
