摘要
目的 了解安徽省肺结核患者的耐药情况。方法 选择 1988～ 1989年和 1998～ 1999年安徽省肺科医院痰培养阳性的住院病人。结果 原发耐药 1998～ 1999年度较 1988～ 1989年度呈上升趋势 ,其中MDR -TB比例高达 5 9.5 2 %。原发耐药明显增多 ,并出现耐 4药病例。结论 由于无管理的化疗导致大量耐药病例产生 ,而对于主要的抗结核药物INH、SM、RFP的耐药直接影响到肺结核病人的治愈率。建议对痰菌阳性病人做痰结核菌培养和药敏试验 ,针对性选择抗痨药物 。
Objective To investigate pulmonary tuberculosis case's drug resistance status in Anhui province.Methods Inpatients of sputum culture positive were selected from Anhui lung hospitalin period of 1988-1989 and 1998-1999.Results A drug resistance trends was higher in 1998-1999 than 1988-1989.Among MDR-TB ratio was 59.52%.Primary resistance distinct raised and patients of resistance 4 drugs had been fended.Conclusion No management chemotherapy results indrug resistance patients.Resistance to INH?SM?RFP make a importance impactedcure rate of pulmonary tuberculosis case.It was suggested that patients of sputum smear positive must to make culture and drug susceptibility test.In order to increased cure rate,antituberculosis's drug were selected was needs.
出处
《安徽医学》
2003年第3期30-31,共2页
Anhui Medical Journal
