摘要
用纯种斯氏艾美耳球虫以6万/只孢子化卵囊的剂量人工感染30～40日龄青紫兰乳兔26只。感染第7d 开始出现死亡,第18～21d 达到高峰。感染第4d,剖检可见肝脏表面病灶,第9d 以后,组织学检查见肝细胞出现灶状坏死。感染的前2周,肝脏以变性和血细胞浸润为主要病变,之后,则以纤维组织和胆管系统和弥漫性增生为特征。自然感染病例也以纤维组织和胆管系统的弥漫性增生为主要病变,同时伴有肝细胞灶性坏死,说明斯氏艾美耳球虫慢性感染的最终结局可能是肝脏纤维化。
Twenty six Chinchilla rabbits,30～40 days old,were infected wi-
th sporulated Eimeria stiedai oocysts 60000 per rabbit.The death of the in-
fected rabbits firstly occurred on the 7th day of infection and reached a peak
between the 18th and 21st day.The lesions on the surface cf the liver were
previously seen on the 4th day,and the focal necrosis of hepatocytes on the
9th day.in the first two weeks of infection,the histopathology of infected
liver was characterized by hepatocyte degeneration and blood cell infiltra-
tion,and then,characterized by hyperplasia of fibrous tissue and bile duct
epithelial cells,the same symptom happened to the field infected rabbits,indi-
cating that fibrosis of infected liver maybe the end—result of chronic Eime-
ria stiedai infection.
出处
《河南农业大学学报》
CAS
CSCD
1992年第1期52-55,共4页
Journal of Henan Agricultural University
关键词
兔
肝球虫
病理学
形态
rabbit
hepatic coccidiosis
pathology
