摘要
S -腺苷甲硫氨酸是生物体内重要的中间代谢物质 ,参与多种生化反应 ,具有广泛和多样的治疗作用 ,但其内在的不稳定性在很大程度上限制了它在临床上的应用。文章主要介绍了S -腺苷甲硫氨酸的失活机理。
S-adenosyl-L-methionine is an important m etabolic intermediate in org anism, which is involved in many biochemical reactions. Its therapeuctic usage c ould be extensive and varied, however its intrinsic instability limit its clini cal application to a large extent. This paper introduce its degradation mechanis m and stabilized theory, also refer to the novel stable salts of S-adenosyl -L-methionine with polyanions.
出处
《药物生物技术》
CAS
CSCD
2003年第2期125-128,共4页
Pharmaceutical Biotechnology
关键词
S-腺苷甲硫氨酸
稳定性
稳定性盐
失活机理
S-adenosyl-L-methionine,Degradation mech anism,Stable salts of SAM with polyanions