摘要
目的 调查 2型糖尿病患者抑郁的患病率 ,分析与抑郁相关的危险因素。 方法 2 2 2例2型糖尿病患者 ,男 115例 ,女 10 7例 ,年龄 ( 5 6± 13)岁 ,病程 ( 7± 6 )年 ,用Zung抑郁自量表进行抑郁评分 ,抑郁指数≥ 0 .5者诊断为抑郁。同时采集身高、体重、体重指数 (BMI)、病程、临床代谢指标、与糖尿病 (DM)有关的健康指标 (如吸烟史、DM家族史等 )。计算抑郁的患病率 ,用非条件Logistic回归筛选抑郁的危险因素。 结果 2 2 2例 2型糖尿病患者中患抑郁者 5 8例。选入Logistic回归方程的变量有 :性别、年龄、民族、婚姻状态、DM家族史、病程、BMI、收缩压、舒张压、空腹血糖、餐后 2h血糖、糖化血红蛋白(HbA1c)、甘油三酯 (TG)、胆固醇 (CH)、高密度脂蛋白 胆固醇 (HDL C)、低密度脂蛋白 胆固醇和并发症数目。进入单因素非条件Logistic回归方程的有 :性别、病程、TG、CH、HbA1c和并发症的数目。进入多因素非条件Logistic回归方程的有病程、性别、HbA1c和并发症的数目。 结论 2型糖尿病抑郁的患病率为2 6 .1% ,性别、病程、HbA1c和并发症的数目是 2型糖尿病合并抑郁的独立危险因素 。
Objective To investigate the prevalence of depression and its risk factors in type 2 diabetics. Methods We conducted a cross sectional study of type 2 diabetics from inpatients and the clinic in our hospital. Zung self rating depression scale (SDS) was used to screen depression in 222 patients [male 115,female 107,aged (56±13)) y, duration of (7±6)y]. Depression was defined when the depression index was more than 0.5. Meanwhile, the demographic data,metabolic data and diabetes related health behaviors were also investigated. Results 58 of 222 type 2 diabetics had depression.Variables selected into the Logistic regression equation included demographic data, diabetes related health behaviors,SBP,DBP,FBG,2 h PBG, HbA 1c , CH,TG,HDL C, LDL C and the number of chronic diabetic complications.Variables went into the unconditional univariate Logistic regression equation included sex, duration,HbA 1c TG,CH and the number of diabetic chronic complications. Variables went into the unconditional multivariate Logistic regression equation included sex, duration, HbA 1c and the number of diabetic chronic complications. Conclusion The prevalence of depression in type 2 diabetics is 26.1%. Sex, duaration, HbA 1c and the number of diabetic chronic complications are independent risk factors of depression, and TG,CH are secondary risk factors of depression.
出处
《中国糖尿病杂志》
CAS
CSCD
2003年第1期46-50,共5页
Chinese Journal of Diabetes
