摘要
目的 了解新生儿缺氧缺血性脑病 (HIE)对患儿远期体格发育和智力发育的影响。方法 对 5 3例经头颅CT及临床表现确诊为HIE的患儿进行了远期随访 ,体格发育用Kaup指数对小儿身高、体重等进行评估 ,智力发育测量用Gesell智能发育量表。结果 HIE与正常儿对照组在体格发育上无显著性差异 (P >0 0 5 ) ,智力低下可发生在中、重度HIE患儿中。结论 降低HIE所致的智残 ,除力争在 5min内建立有效呼吸和完善的循环功能外 ,还要重视复苏后心、肾、脑的保护。
Objectives:To investigate the long-term effect of hypoxic-ischemic encephalopathy (HIE) on physical growth and mental development.Methods:Long-term following-up were performed on 53 cases of HIE confirmed by cranial CT and clinical manifestations.The physical growth,including height and weight,were evaluated with Kaup indexes,and mental development was assessed by Gesell intelligent development measure.Result:Compared with the control group which consisted of normal children,children with HIE shown no obvious difference in physical growth,(P>0.05) while mental deficiency mostly occurred in those with moderate and serious HIE.Conclusions:To reduce the incidence of mental deficiency caused by HIE,spontaneous breath should be founded in less than 5 minutes,protection of heart,kidneys and brain after resuscitation should be emphasized and children with HIE should be treated as early ss possible.
出处
《中国优生与遗传杂志》
2003年第2期79-80,共2页
Chinese Journal of Birth Health & Heredity
