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认知障碍与脑损害部位的相关研究 被引量:29

Study of the correlation between the cognitive dysfunction and the locus of brain lesion
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摘要 目的 明确认知障碍与脑损害部位是否有必然的联系 ,探索不同的认知障碍在脑部相应区域的定位。方法 采用中文版神经行为认知测试 (NCSE)量表测试脑部损害后有认知障碍的患者 30例 ,将其脑部损害的CT定位与NCSE的 10个分项目 (ORI、ATT、COMP、REP、NAM、CONST、MEM、CALC、SIM、JUD )进行相关分析。结果 左、右侧均与COMP相关 (P <0 .0 5 ) ;额叶与CALC、JUD、MEM相关 (P值分别为 <0 .0 5及 <0 .0 1) ;顶叶与NAM、JUD相关 (P <0 .0 5 ) ,与REP、CALC明显相关 (P <0 .0 1) ;颞叶和基底节与各项分测验均不相关 (P >0 .0 5 )。结论 认知障碍与脑病损部位有关 ,以额。 Objective To define whether there exists correlation between the cognitive dysfunction and the locus of brain lesion and to map the localization of brain lesions for different cognitive dysfunction. Methods Cognitive function was tested with NCSE in 30 patients with cognitive dysfunction caused by brain lesion. Correlation between the locus of brain lesion and cognitive dysfunction was tested and analyzed with CT scan and 10 items (ORI, ATT, COMP, REP, NAM, CONST, MEM, CALC, SIM and JUD) of the NCSE. Results The lesions of either side of brain were related to COMP, while the frontal lobe was related to CALC, JUD and MEM; lesions of the parietal lobe were related to NAM, JUD and especially to the item of REP and CALC (P<0.01). No significant relation was revealed between temporal or basilar lesions with the above-mentioned items(P>0.05). Conclusion Cognitive dysfunction is related to the locus of brain lesion, and this is especially true for lesions in the frontal and parietal lobes.
出处 《中华物理医学与康复杂志》 CAS CSCD 北大核心 2003年第4期223-225,共3页 Chinese Journal of Physical Medicine and Rehabilitation
基金 卫生部科学研究基金项目 (NO .98 1 1 2 8)
关键词 认知障碍 脑损害部位 神经行为认知测试 统计学分析 额叶 Cognitive dysfunction NCSE Brain lesion
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