摘要
目的 用小鼠肝细胞彗星实验检测生活饮用水氯化消毒前后的诱变性。方法 采用彗星实验分别对泸州市南郊水厂的水源水、出厂水、自来水的有机浓集物的诱变性进行检测。结果 水源水的有机浓集物的彗星实验在高剂量组 (相当于原水样量 5 0 0ml)才出现阳性 ,而出厂水、自来水的彗星实验在较低剂量组 (相当于原水样量 10 0ml)呈阳性反应。结论 水源水和氯化消毒饮用水都能诱导动物细胞DNA损伤 ,说明水源水和氯化消毒饮用水里存在致突变物质 ,2者对人类健康都存在潜在的威胁 。
Objective To Study the effects of organic extracts from drinking water on human heaths Methods The effects of organic extracts from all the water samples of luzhou city on DNA damage in mouse Primary Cell were observed with comet assay Results The organic extracts from the sample of source water could not cause DNA damage in mouse Primary Cell, but the organic extracts from both the samples of drinking water and c hlorinated water could Conclusion The effects of organic extracts from drinking water on DNA damage were inhanced by chlorination
出处
《预防医学情报杂志》
CAS
2003年第2期116-117,共2页
Journal of Preventive Medicine Information
关键词
有机提取物
饮用水
肝原代细胞
DNA损伤
彗星实验
Organic extracts
Drinking water
Hepatocytes primary cell
DNA damage
Comet assay
