摘要
目的:比较小儿术前口服咪唑安定氯胺酮阿托品混合液与常规方法肌注安定阿托品的临床效果。方法:择期行小儿泌尿外科手术的男性小儿40例,随机分为2组。观察指标:对术前药的接受程度、给药后的血氧饱和度、镇静状态评分、与父母分离程度和静脉穿刺时的反应、对面罩的接受程度、苏醒时间以及术后并发症。结果:肌肉注射给药65％小儿不能接受、哭闹,给药30 min后,与父母难分离,静脉穿刺及麻醉诱导不平稳。口服组用药30min后,小儿安静、合作,易与父母分离,静脉穿刺及麻醉诱导无抵抗,两组差异显著(P<0.01)。结论:小儿术前口服咪唑安定氟胺酮阿托品混合液的临床效果优于常规传统方法肌注安定阿托品,是较为理想的麻醉前用药。
Objective: Our aim was to compare the clinical effects of oral premedicant of mixture of midazolam, ketamine and atropine with muscle injection of valium and atropine in children. Methods: Forty boys scheduled for urinary surgery were randomly divided into 2 groups. Following indexes were observed: acceptance level to premedicant;SpO2 after premedication; sedation scores; reaction to separation with parents and venous puncture and face mask; awake time; complications after operation. Results: Sixty-five percentage children could not accept muscle injection. They cried and struggled. Thirty minutes after premedication, it was hard for those received muscle injection to be separated with parents and to accept venous puncture and face mask. In oral intake group, children became calm and cooperative thirty minutes after premedication. Venous puncture and anesthesia induction became easy. The difference between the 2 groups was significant ( P < 0.01). Conclusion:The clinical effects of oral premedicant of mixture of midazolam, ketamine and atropine was better than those of muscle injection of valium and atropine in children,so it is a. comparatively ideal premedication.
出处
《中国医科大学学报》
CAS
CSCD
北大核心
2003年第2期165-166,共2页
Journal of China Medical University
