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舒必利治疗咽异物感的临床研究

The clinical study of sulpride of small dose in the treatment of foreign body sensation of pharynx
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摘要 目的 观察舒必利治疗咽异物症的疗效。方法 治疗组在常规治疗基础上 ,加用舒必利治疗 ,舒必利剂量 2 0 0~ 40 0mg/日。结果 治疗组治愈率 (75 .2 % )和总有效率 (89.0 % )均高于对照组 (38.9% ,68.5 % ) ,并有显著性差异 ,且治疗组在SCL 90、HAMA、HAMD的治疗前后评分方面有显著性差异。两组治疗的副作用轻微 ,仅治疗组少数病例用药后出现失眠、皮疹、月经不调等。结论 在常规咽侧索封闭治疗的基础上 ,联用舒必利治疗咽异物症安全有效 。 Objective To observe the clinical effects of sulpride of small dose in the treatment of foreign body sensation of pharynx. Methods 217 patients with foreign body sensation of pharynx were randomly divided into two groups: study group and control group. Control group (108 cases) were treated with conventional lutation therapy in the lateral pharyngeal bands (CLTLPB), once a week, the course is four weeks; study group (109 cases) were treated with the combination of CLTLPB and oral sulpride (200~400mg/d). Results The healing rate and the improvement rate for the study group (75.2%, 89.0% respectively) were significantly higher than that of control group (38.9%, 68.5% respectively). After treatment the scores of SCL 90, HAMA, and HAMD for study group were significantly lower than before treatment. The side effects for the two groups were minor, except that a few patients in study group were observed to have insomnia, skin eruption, and menoxenia et al. Conclusions Based on the treatment with CLTLPB, the augmentation of sulpride is a safe and effective method for treating foreign body sensation of pharynx, and is worthy of being extended into clinical practice.
机构地区 解放军
出处 《中国行为医学科学》 CSCD 2003年第1期64-65,共2页 Chinese Journal of Behavioral Medical Science
关键词 舒必利 咽异物症 焦虑抑郁 疗效 副作用 Sulpride Foreign body sensation of pharynx Anxiety/Depression Efficacy analysis
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