IGF—1、IGF—BP—1、IGF—BP—3与糖尿病及糖尿病微血管并发症
摘要
糖尿病影响循环中胰岛素样生长因子的水平和活性,不同类型的糖尿病对胰岛素样生长因子活性的影响是不同的。糖尿病患者体内胰岛素样生长因子的紊乱,可能参与糖尿病肾病、糖尿病视网膜病变的发生、发展。胰岛素样生长因子结合球蛋白-1可能对微血管病变起保护作用,胰岛素样生长因子结合球蛋白-3参与微血管病变的发病机制不明。
出处
《国外医学(老年医学分册)》
2003年第3期112-114,共3页
Foreign Medical Sciences(Geriatrics)
参考文献8
-
1Garay- sevilla ME, Nava LE, Malacara JM et al. Advanced glycosytation and products (AGES). insulin- llke growth factor- 1 and IGF- binding protein- 3 (IGFBP- 3 ) in patients with type 2 diabetes mellitus. Diabetes Metab Res Rev. 2000:16 (2): 106-113.
-
2Chiarelli F, Sartilli F, Mohn A. Role of growth factors in the devdopment of diabetic comaplications. Horm Res, 2000; 53(2) : 53-67.
-
3Krsek M, Prazny M, Skrha J et al. IGFBP- 1 and its protective role in the pathogenesis of microangiopathy in type 1 diabetes mellitus. Cas Lek Cesk, 2001; 140.
-
4Lupia E, Elliot SJ. IGF- 1 decrease collagen degradation in diabetic NOD mesangial cells: complications for diabetic nephropathy. Diabetes, 1999; 48. 1638-1644.
-
5Janssen JA, Lamberts SW. Circulating IGF- 1 and its protective role in the pathogenesis of diabetic angiopathy. Clin Endocrinol, 2000; 52 (1): 1-9.
-
6Barkai K, Tombac ZA. Altemation in insulin- like growth factor binding protein- 1 and sex hormone binding globulin levels in type 1 diabetic adolescents with microalbuminuria.Diabetes Care, 2001; 24 (3): 605-606.
-
7Verrotti A, Cieri F, Petitti MT et al. Growth hormone and IGF - 1 in diabetic children with and without microalbuminuria Diabetes Nutr Metab, 1999; 12 (4):271-276.
-
8Spranger J , Buhnan J , Jansen V et al . Systemic levels contribute significantly to increased intraocular IGF- 1、IGF-2 and IGF- BP3 in proliferative diabetic reinopathy. Horm Metab Res, 2000; 32 (5): 196 - 200n the pig eye.Ophthalmology. 1997:104 (10): 1661-1669.
-
1李翠英.IGF-1、IGF-BP-1、IGF-BP-3与糖尿病肾病[J].实用老年医学,2005,19(6):318-320. 被引量:1
-
2胡蜀红,蔡仕林.男性Ⅱ型糖尿病患者胰岛素敏感性与性激素结合球蛋白浓度相关性研究[J].中国糖尿病杂志,1997,5(2):95-98. 被引量:2
-
3郭芝生,陈达力.甲状腺机能亢进症患者治疗前后血清性激素结合球蛋白结合...[J].中华内科杂志,1993,32(4):243-245. 被引量:3
-
4刘翠平,支忠继,卢立华,李跃林.NIDDM老年患者胰岛素敏感性与性激素[J].河北医学,1997,3(6):85-86.
-
5李秋生.性激素结合球蛋白与绝经后女性冠心病关系的探讨[J].实用预防医学,2010,17(1):88-90. 被引量:6
-
6王兴木,官莉莉.2型糖尿病大血管病变患者血浆ET水平与临床[J].放射免疫学杂志,2008,21(3):227-228. 被引量:3
-
7武革,沈更新,赵玉兰,揭育丽,谢英才,甄卓丽.肥胖与非肥胖男性2型糖尿病患者性激素结合球蛋白与胰岛素抵抗关系的探讨[J].中华内分泌代谢杂志,1999,15(4):251-252. 被引量:6
-
8张贝,李成江.胰岛素样生长因子与糖尿病脑病[J].国外医学(老年医学分册),2006,27(4):181-185.
-
9李春梅,林华棒,朱诗呈.HCY与SHBG联合检测在糖尿病肾病早期的应用研究[J].医药前沿,2016,0(1):117-118.
-
10丁少芳.甲状腺功能异常时血清性激素结合球蛋白的变化[J].云南医药,1994,15(5):386-387. 被引量:1