摘要
主动脉内气囊反搏是当今世界的通用心脏辅助装置,其气囊的结构和造型是影响治疗效果的关键因素之一。为探讨气囊的几何造型与反搏效果的关系,本文用数学模型和数字计算机仿真的方法,对于双气囊式主动脉内气囊反搏的结构和造型与反搏效果的关系进行了研究,其中包括前后两气囊的体积比例的选取、两气囊充排气时相的设置等。仿真实验结果表明,若选择后囊小、前囊大的结构,且当后囊体积占总体积的40%左右时,同时采取后囊较前囊早充气晚排气的控制方式时,可取得最佳反搏效果。如用冠脉血流量或主动脉平均舒张压等生理指标来评价反搏效果,则优化设计和控制下的双囊反搏较单囊反搏的效果可提高20%左右。
Intraaortic Balloon Pumping (IABP) is a kind of cardiac assist device widely used all over the world. The balloon configuration and structure are important for the effectiveness of the IABP. A mathematical model and computer simulation method were used to study the effects of different configurations and controls of a proposed double chamber IABP balloon. The study included the selection of volume ratio and the inflation and deflation timing of the two chambers. Simulation results showed that optimal assistance of the IABP to the heart can be achieved when the configuration and control of the balloon were chosen to have the following features: the front chamber is larger than the rear one, the rear chamber's volume is 40 of the total volume, and the rear chamber is inflated ahead of the front one and deflated after the front one. When total coronary flow and mean diastolic aortic pressure were taken as the indications of effectiveness of IABP, the double chamber balloon under optimal design and control can provide about 20 more assistance than the single chamber IABP.
出处
《航天医学与医学工程》
CAS
CSCD
1992年第1期7-12,共6页
Space Medicine & Medical Engineering
关键词
心脏起搏器
设计
仿真
主动脉
cardiac pacemakers, optimal design, simulation
