摘要
目的 探讨婴幼儿体外循环 (CPB)术后继发癫痫的临床特征、治疗和预防。方法 1995 - 0 5～ 2 0 0 2 - 0 5对 2 0例婴幼儿先心病CPB术后继发癫痫的年龄、脑电图 (EEG)、MRI等方面进行分析综合。结果 2 0例中 ,男 14例 ,女 6例。首发年龄 :2个月～ 14岁 ,平均 4岁 2个月 ;其中小于 6岁的婴幼儿多在CPB术后 7d发病。微小发作 (minimalseizure)及全身发作分别8例和 5例。脑电图显示 1周后多呈局限性或弥漫性慢波 ,异常放电波增多。 6例行MRI检查提示局限性T2 信号增强。结论 婴幼儿发病较早 ,年龄大者发病较晚 ,EEG及MRI有助于早期诊断和预后判断 。
Objective To summarize clinical features and therapeutic experience and preventation of epilepsy after cardiopulmonary bypass. Methods Twenty patients with epilepsy after surgery were retrospectively analyzed. The causes, preventation, treatment and diagnosis of epilepsy were fully evluated by using EEG, MRI and other clinical data. Results Twenty patients(14 males, 6 females)were studied. The onset ages of seizure were between 2 months and 14 years with an average of 4 years and 2 months. First seizure occurred mostly in the 7 days after surgery for patients less than 6 years. Minimal and generalized seizures occured in 8 and 5 patients, respectively. Electroencephalogram(EEG)revealed focally slow-waves and epileptic discharges which were apparently increased in day 7 after surgery. MRI suggested enhanced T 2-weighted spots in 6 cases. Conclusion Epilepsy after surgery with CPB occurs earlier in infants and later in the older children. EEG plays an important role in the early diagnosis and detection of subclinical epilepsy which might be valuable for assessing later prognosis.MRI has a high predictive value for epilepsy.
出处
《山西医科大学学报》
CAS
2003年第2期153-154,共2页
Journal of Shanxi Medical University
