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阿托伐他汀和吉非贝齐治疗老年人高脂血症的疗效比较 被引量:3

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摘要 目的:比较阿托伐他汀和吉非贝齐治疗老年人高脂血症的疗效。方法:40例老年高脂血症患者随机分为阿托伐他汀(治疗组)组和吉非贝齐组(对照组),每组20例。阿托伐他汀口服10mg/d,吉非贝齐口服60Omg,每日2次,疗程均为4周。结果:治疗4周末血总胆固醇(TC)、甘油三酯(TG)及低密度脂蛋白胆固醇(LDL-c)与基线水平比较,两组均有明显下降(P<0.05,P<0.01或P<0.001);高密度脂蛋白胆固醇(HDL-c)有明显升高(P<0.01);治疗组降低TC及 LDL-c疗效明显优于对照组(P<0.01和P<0.001),降低TG及升高HDL-c疗效和对照组无明显差异(P>0.05)。两组均未见明显副作用。结论:阿托伐他汀在降低TC,TG,LDL-c及升高HDL-c方面有很好疗效,无明显副作用,适用于老年患者。
出处 《中国药业》 CAS 2003年第3期69-70,共2页 China Pharmaceuticals
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同被引文献17

  • 1赵水平.强化降脂治疗的临床应用和意义[J].基础医学与临床,2006,26(2):113-117. 被引量:14
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