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小牛血去蛋白提取物对胃溃疡患者的疗效评价 被引量:9

Efficacy of deproteinised calf blood extract in treatment of patients w ith peptic ulcer disease
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摘要 目的 :探讨小牛血去蛋白提取物 (DCBE)对胃溃疡的治疗作用。方法 :选择年龄 2 0~ 70岁之间 ,经胃镜检查确诊为活动期胃溃疡的住院患者 60例。治疗组 3 2例采用静脉滴注DCBE (80 0mg,qd)和法莫替丁 (1 0 0mg,bid)治疗 ;对照组 2 8例采用静脉滴注法莫替丁 (1 0 0mg,bid)单独治疗。用药 2、4wk行胃镜检查 ,观察自觉缓解症状、时间、愈合率和总有效率。结果 :治疗组自觉症状缓解时间明显缩短 ;给药后 2、4wk治疗组及对照组胃镜检查溃疡愈合率分别为 78.1 % ,46.4%及 84.4% ,71 .4%。结论 AIM: To observe the efficacy of deproteinise d calf blood extract (DCBE) in the treatment of patients with peptic ulcer disease . METHODS: 60 patients were randomly divided into two groups. Tr eating group (n=32) received DCBE (800 mg, qd) and famotidine (1 00 mg, bid) and control group (n=28) received famotidine (100 mg /bid). These treatments lasted for four weeks. The efficacy was determined by ga stroendoscopy. RESULTS: The ulcer healing rates were 78.1 % and 46.4 % for 2 wk, and 84.4 % and 71.4 % for 4 wk in treating grou p and control group, respectively. CONCLUSION: DCBE has a signif icant effect in the treatment of patients with peptic ulcer disease.
出处 《中国临床药理学与治疗学》 CAS CSCD 2003年第3期314-316,共3页 Chinese Journal of Clinical Pharmacology and Therapeutics
关键词 小牛血去蛋白提取物 胃溃疡 疗效 药效学 法莫替丁 pharmacodynamics deproteinised calf blood extract famotidine peptic ulcer
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