摘要
[目的 ]考察剥除与不剥除糖衣进行糖衣片含量测定的差异。 [方法 ]采用数学分析方法 ,证明在包衣物质对含量测定方法无干扰的情况下 ,剥除与不剥除糖衣进行含量测定在理论上存在着差异。 [结果 ]剥除糖衣后 ,片心的损失会造成含量测定结果偏低 ,而糖衣的残留不会影响含量测定结果。 [结论 ]在包衣物质不影响含量测定的条件下 。
AIM]To investigate the differ ence between the assays of coated tablets with removed coating or without remove d coating. [METHODS]It was proved by mathematical analysis that the re was a theoretical differece between the assays of coated tablets with removed coating or without removed coating, under the condition of no influence of coat ing matericals on the assay. [RESULTS]After removing coating, the assaying result attenuated because of the loss of the tablet core, meanwhile th e residual coating had no influence on the assaying result. [CONCLUSION] When coating materials dont interfere with the assay of coated tablets, the direct assay without removed coating is feasible.
出处
《药学进展》
CAS
2003年第2期108-109,共2页
Progress in Pharmaceutical Sciences
