摘要
目的 评估幽门螺杆菌粪便抗原 (HpSA)试验诊断儿童幽门螺杆菌 (Hp)感染的准确性。 方法 收集31例接受13 C 尿素呼气试验 (13 C UBT)检查 2日内患儿的粪便标本 ,应用酶免疫反应原理进行HpSA试验 ;以13 C UBT作为诊断标准。结果 以光密度值≥ 0 12 1为阳性 ,HpSA检测诊断Hp感染的敏感性 86 6 7%、特异性93 78%、阳性预测值为 92 86 %、阴性预测值 88 2 4 %和准确性 90 32 %。结论 HpSA检查是一种简便、非侵入性的诊断儿童Hp感染的一种方法。
Objective To evaluate the accuracy of the Helicobacter pylori stool antigen (HpSA) test for detection of Helicobacter pylori infection in children.Methods Stool specimens were collected from 31 consecutive patients (4～14 years) who received 13 C Urea Breath Test within 2 days for gastrointestinal symptoms.The evaluation of Helicobacter pylori status was defined as positive when 13 C Urea Breath Test were positive.Results The sensitivity of HpSA test for the diagnosis of Helicobacter pylori using a cutoff value of 0 121% was 86 67% and its specificity was 93 78%.The positive predictive and negative predictive value were 92 86% and 88 24%,respectively,and accuracy 90 32%.Conclusion HpSA test is simple,noninvasive and highly accurate test for the diagnosis of Helicobacter pylori infection in children.
出处
《中国实用儿科杂志》
CSCD
北大核心
2003年第4期226-227,共2页
Chinese Journal of Practical Pediatrics
