摘要
研究重组人干扰素α-2b(商品名:安福隆)的稳定性.采用细胞病变法(CPE)检测在4℃贮存条件下放置不同时段的干扰素α-2b水针、粉针和干扰素标准品的抗病毒能力,与标准品比较,评价了水针和粉针的稳定性.结果显示,在4℃的贮存条件下,干扰素α-2b水针和粉针的抗病毒能力基本相同;经两年贮存后,也没有明显地变化,且均比标准品抗病毒能力强.说明干扰素α-2b水针和粉针稳定性均较好,其辅料配方合理,可有效保护干扰素α-2b,减少其降解.
In order to evaluate the stability of injection and powder form of interferon α2b, the cytopathogenic effect (CPE) was applied to assay the antiviral activity of them that stored for different periods of time at 4℃, and compared with those of standard interferon. The results showed that injection and powder are of the same antiviral activity even though after two years of storage, and showed better protective effect on cells than that of standard interferon. It demonstrated the stability of injection and powder form of interferon α2b are reliable.
出处
《天津师范大学学报（自然科学版）》
CAS
2003年第1期43-45,共3页
Journal of Tianjin Normal University：Natural Science Edition
