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登革病毒疫苗研究近况 被引量：1

Advances in Dengue virus vaccine
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摘要 本文回顾了近年来登革病毒ＤＮＡ疫苗、嵌合疫苗、重组亚单位疫苗、四价减毒活疫苗等方面的研究进展．阐述了各种疫苗的动物免疫保护作用。
作者 魏惠永
机构地区 广东省人民医院
出处 《热带医学杂志》 CAS 2001年第1期72-76,79,共6页 Journal of Tropical Medicine
关键词 登革热 蚊煤传染病 登革病毒 疫苗
分类号 R512.8 [医药卫生—内科学]
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参考文献19

  • 1Kochel T, Wu S J, Raviprakash K, et al. Inoculation of plasmids expressing the dengue-2 envelope gene elicit neutralizing antibodies in mice. Vaccine, 1997; 15: 547-552
  • 2Porter KR, Kochel T, Wu SJ, et al. Protective efficacy of a dengue 2 DNA vaccine in mice and the effect of CpG immuno- stimulatory motifs on antibody responses. Arch Virol, 1998; 143:997 - 1003
  • 3Konishi E, Yamaoka M, Kurane I, et al. A DNA vaccine expressing dengue type 2 virus premembrane and envelope genes induces neutralizing antibody and memory B cells in mice. Vaccine, 2000; 18:1133 - 1139
  • 4Raviprakash K, Kochel T, Ewing D, et al. Immunogenicity of dengue virus type 1 DNA vaccines expressing trucated and full length envelope protein. Vaccine, 2000; 18:2426 - 2434
  • 5Raviprakash K, Porter KR, Kochel T, et al. Dengue virus type 1 DNA vaccine induces protective immune responses in rhesus macapue. J Gen Virol, 2000; 81:1659 - 1667
  • 6Kochel TJ, Raviprakash K, Hayes CG, et al. A dengue virus serotype- 1 DNA vaccine induces virus neutralizing antibodies and provides protection from viral challenge in Aotus monkeys. Vaccine, 2000; 18:3166 -3173
  • 7Chen W, Kawano H, Men R, et al. Construction of intertypic chimeric dengue viruses exhibiting type 3 antigenicity and neurovirulence for mice. J Virol, 1995; 69: 5186-5190
  • 8Bray M, Men R, Tokimatsu I, et al. Genetic determinants responsible for acquisistion of dengue type 2 virus mouse neurovirulence. J Virol, 1998; 72:1647 - 1651
  • 9Butrapet S, Huang CY, Pierro DJ, et al. Attenuation markers of a candidate dengue type 2 vaccine virus, strain 16681(PDK-53), are defined by mutions in 5' noncoding region and nonstructural protein 1 and 3. J Virol,2000; 74(7): 3011 -3019
  • 10Huang CY, Butrapet S, Pierro DJ, et al. Chimeric dengue type 2(vaccine strain PDK-53)/dengu' type 1virus as a potential candidate dengue type 1 virus vaccine.J Virol, 2000; 74(7): 3020-3028

同被引文献30

  • 1Rovers MM,Schilder AG,Zielhuis GA,Rosenfeld RM,张江平,杨妙丽,张全安.中耳炎[J].国外医学（耳鼻咽喉科学分册）,2005,29(3):141-143. 被引量：442
  • 2王军军,任瑞文,田小东,方美玉,洪文艳.广州登革病毒1型NS2a-NS2b基因序列分析[J].热带医学杂志,2005,5(4):424-426. 被引量：3
  • 3方丹云,周经姣,黄骥斌,韩艳平,江丽芳.登革病毒流行株的分离鉴定及其毒力位点变异研究[J].生物技术,2006,16(2):26-27. 被引量：7
  • 4HALSTEAD SB.Pathogensis of dengus:challengees to molecular biology[J].Science,1988,239:476-481.
  • 5ROSEN L.The emperor's new clothes revisited or reflections on the pathogensis of dengue hemorrhagic fever[J].Am J Trop Med Hyg,1977,26:337-343.
  • 6BIELEFELDT-OHMANN H.Pathogenesis of dengue virus diseases:missing pieces in the jigsaw[J].Trends Microbiol,1997,5 (10):409 -413.
  • 7PURI B,NEISON WM,HENCHAL EA,et al.Molecular analysis of dengue virus attenuation after serial passage in primary dog kidney cells[J].Gen Virol,1997,78:2287-2291.
  • 8BRAY M,LAI CJ.Construction of intertypic chimeric dengue viruses by substitution of structural protein genes[J].Proc Natl Acad Sci USA,1991,88(22):10342-10346.
  • 9KAWANOH ROSTAPSHOVV ROSENL etal.Genetic determinants of dengue type 4 virus neurovirulence for mice 《热带医学杂志》简介[J].J Virol,1993,67:6567-6575.
  • 10CAHOUR A,PLETNEV A,VAZIELLE-FALCOZ M,et al.Growth-restricted dengue virus mutants containing deletions in the 5' noncoding region of the RNA genome[J].Virology,1995,207(1):68-76.

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热带医学杂志
2001年 第1期

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